简介
万鹏霞,女,副主任医师,博士医疗特长:从事眼科临床医疗、教学和科研工作16年,对角膜与眼表疾病、泪道疾病、白内障、青光眼、眼外伤及眼底病的诊断与治疗有丰富的临床经验,擅长角膜移植术、翼状胬肉切除术、泪道再通术、白内障超声乳化吸除联合人工晶体植入术、抗青光眼手术及玻璃体视网膜手术。研究方向:角膜与眼表疾病、干细胞与组织工程角膜、眼表疾病的细胞治疗等相关研主要教育和工作经历:本科毕业于北京大学临床医学专业,于中山大学攻读取得眼科学硕士、博士学位,美国康奈尔大学眼科研究学者。博士毕业后于中山大学中山眼科中心工作,2014年调入本院至今。社会兼职:中国生物医学工程学会组织工程与再生医学分会青年委员广东省医院协会医院眼健康管理专业委员会常务委员广东省视光学会理事广东省残疾人康复协会视力残疾康复专业委员会常委广东省低视力康复技术指导中心副主任广东省医师协会眼科分会委员广东省医疗行业协会眼科管理分会委员广州市医师协会青年医师分会委员论著:1. Wan P, Wang X, Ma P, Gao N, Ge J, Mou Y, Wang Z. Cell delivery with fixed amniotic membrane reconstructs corneal epithelium in rabbits with limbal stem cell deficiency. Invest Ophthalmol Vis Sci. 2011; 9; 52(2):724-30. (IF=3.466)2. Wan PX, Wang BW, Wang ZC. Importance of the stem cell microenvironment for ophthalmological cell-based therapy. World J Stem Cells 2015; 7(2): 448-460.3. Chenjing Zhou, Zheqian Huang, Panlong Li, Weiqiang Li, Ying Liu, Chaoyang Li, Zhao Liu, Xiaoran Wang, Pengxia Wan(Co-corresponding author), zhichong wang. Safety and Efficacy of Embryonic Stem Cell Microenvironment in a Leukemia Mouse Model. Stem Cells and Development. 2014, 23(15): 1741-1754. ?.(IF=4.67)4. Liu Z, Wan P, Duan H, Zhou J, Tan B, Zhou Q, Zhou C, Huang Z, Tian B, Li C, Wang Z. ES micro-environment enhances stemness and inhibits apoptosis in human limbal stem cells via the maintenance of telomerase activity. PLOS ONE, 2013; 8(1):e53576. doi: 10.1371/journal.pone.0053576. (IF=3.73 )5. Zheng D, Wan P, Liang J, Song T, Liu Y. Comparison of clinical outcomes between iris fixated anterior chamber intraocular lenses and scleral fixated posterior chamber intraocular lenses in Marfans syndrome with lens subluxation. Clin Experiment Ophthalmol. 2012; 40(3):268-74. (IF=1.766)6. Li N, Wang X, Wan P, Huang M, Wu Z, Liang X, Liu Y, Ge J, Huang J, Wang Z. Tectonic lamellar keratoplasty with acellular corneal stroma in high-risk corneal transplantation. Mol Vis. 2011; 17: 1909-17. (IF=2.511)7. M Huang, B Wang,, P Wan, X Liang, XWang, Y Liu, Q Zhou, Z Wang.The roles of the limbal microvascular net and the limbal stroma in regulating the maintenance of limbal epithelial stem cells. Cell and tissue research.. 2015, 359(2):547-563 (IF=3.677)8. Chen D, Li N, Wan P, Xiao J, Liu Y, Wang X, Wang Z. A novel procedure for treating canalicular obstruction by re-canaliculisation and bicanalicular intubation. Br J Ophthalmol. 2011; 7. (IF=2.934)9. Liu Z, Zhuang J, Li C, Wan P, Li N, Zhou Q, Zhou C, Huang Z, Wang Z. Long-term cultivation of human corneal endothelial cells by telomerase expression. Exp Eye Res. 2012 Jul; 100:40-51. (IF=3.026 )10. Li C, Song Y, Luan S, Wan P, Li N, Tang J, Han Y, Xiong C, Wang Z. Research on the stability of a rabbit dry eye model induced by topical application of the preservative benzalkonium chloride. PLoS One. 2012; 7(3):e33688. (IF= 4.092)11. Huang M, Li N, Wu Z, Wan P, Liang X, Zhang W, Wang X, Li C, Xiao J, Zhou Q,Liu Z, Wang Z. Using acellular porcine limbal stroma for rabbit limbal stem cell microenvironment reconstruction. Biomaterials. 2011; 32(31):7812-21. (IF=7.882)12. Zhang W, Xiao J, Li C, Wan P, Liu Y, Wu Z, Huang M, Wang X, Wang Z. Rapidly constructed scaffold-free cornea epithelial sheets for ocular surface reconstruction. Tissue Eng Part C Methods. 2011; 17(5):569-77. (IF=4.697)13. Zhou Y, Wu Z, Ge J, Wan P, Li N, Xiang P, Gao Q, Wang Z. Development and characterization of acellular porcine corneal matrix using sodium dodecylsulfate. Cornea. 2011; 30(1):73-82. (IF=1.762 )14. Liu Z, Zhou Q, Zhu J, Xiao J, Wan P, Zhou C, Huang Z, Qiang N, Zhang W, Wu Z, Quan D, Wang Z. Using genipin-crosslinked acellular porcine corneal stroma for cosmetic corneal lens implants. Biomaterials. 2012 Oct;33(30):7336-46. (IF=7.604 )15. Ke Q, Wang X, Gao Q, Wu Z, Wan P, Zhan W, Ge J, Wang Z. Carrier-free epithelial cell sheets prepared by enzymatic degradation of collagen gel. J Tissue Eng Regen Med. 2011;5(2):138-45. (IF=3.534)16. Zhou J, Chen F, Xiao J, Li C, Liu Y, Ding Y, Wan P, Wang X, Huang J, Wang Z. Enhanced functional properties of corneal epithelial cells by coculture with embryonic stem cells via the integrin β1-FAK-PI3K/Akt pathway. Int J Biochem Cell Biol. 2011; 43(8):1168-77. (IF=4.956)17. Liu Y, Ding Y, Ma P, Wu Z, Duan H, Liu Z, Wan P, Lu X, Xiang P, Ge J, Wang Z.Enhancement of long-term proliferative capacity of rabbit corneal epithelial cells by embryonic stem cell conditioned medium. Tissue Eng Part C Methods. 2010;16(4):793-802. (IF=4.697)18. Lu X, Chen D, Liu Z, Li C, Liu Y, Zhou J, Wan P, Mou YG, Wang Z. Enhanced survival in vitro of human corneal endothelial cells using mouse embryonic stem cell conditioned medium. Mol Vis. 2010; 8; 16:611-22. (IF=2.541)19. Yan L, Wu W, Wang Z, Li C, Lu X, Duan H, Zhou J, Wang X, Wan P, Song Y, Tang J, Han Y. Comparative Study of the Effects of Recombinant Human Epidermal Growth Factor and Basic Fibroblast Growth Factor on Corneal Epithelial Wound Healing and Neovascularization in vivo and in vitro. Ophthalmic Res. 2012 Dec 18;49(3):150-160. (IF=1.562 )20. Wu Z, Zhou Q, Duan H, Wang X, Xiao J, Duan H, Li N, Li C, Wan P, Liu Y, Song Y, Zhou C, Huang Z, Wang Z. Reconstruction of auto-tissue-engineered lamellar cornea by dynamic culture for transplantation: a rabbit model. PLoS One. 2014 Apr4;9(4):e93012. doi: 10.1371/journal.pone.0093012. eCollection 2014. (IF= 4.092)21. 万鹏霞,王晓然,宋亦悦等. 氯替泼诺治疗干眼的疗效观察,中华眼科杂志,2012,48(2):1-6.22. 万鹏霞,王智崇,马萍等.羊膜接触镜输送人表皮干细胞重建兔角膜上皮,中华生物医学工程杂志,2009,(1):14-19.23. 万鹏霞,李乃洋,鹿晓燕,王智崇.12例泪小管炎临床分析,广东医学,2010,31:20-22.24. 万鹏霞,李乃洋,刘钊,鹿晓燕,王智崇. 球结膜松弛矫正术的疗效分析.广州医学院学报,2010,38(3):102-105.25. 万鹏霞,何志恒,汪振芳.组织粘合剂在翼状胬肉切除联合羊膜移植术中的应用,眼科学报,2005,4:105-109.26. 万鹏霞,佘守章,张本国.星状神经节阻滞治疗低灌注性视网膜病变,广东医学,2005,26(9):1218-1219.27. 李乃洋,王晓然,万鹏霞等.高危角膜移植排斥兔模型的建立及对比研究.中华实验眼科杂志,2012,30(1).28. 汪振芳,万鹏霞,何丽文,等.大鼠视网膜下注射Matrigel诱导视网膜色素上皮易位和脉络膜新生血管形成,中华生物医学工程杂志,2007,13(6):345-348.29. 李强,万鹏霞.翼状胬肉切除术后应用贝复舒与爱丽滴眼液疗效对比观察,临床眼科,2005,13(3):242.30. 李强,万鹏霞.非穿透小梁切除术联合丝裂霉素C及羊膜植入术治疗难治性青少年开角型青光眼,河北医学,2005,11(7):579.31. 李强,万鹏霞.慢性泪囊炎三种手术方式临床观察,眼外伤职业眼病杂志,2005,27(5):347-349.32. 何志恒,万鹏霞.巩膜隧道式切口白内障摘除人工晶体植入术68例临床分析,实用医学,2005,21:64-65.专著:《眼科手术技术(第二版)》. 北京, 科学出版社, 2012.其他主要工作成绩(比如获奖情况):主持国家自然科学基金、广东省科技计划、广东省自然科学基金、广东省医学科研基金、国家重点实验室青年引导课题、广东省生物医学工程重点实验室开放基金项目、中山大学青年教师培育计划共8项,参与“十一五”、“十二五”国家高技术研究发展计划(863计划)、“十一五”国家科技支撑计划、国家自然科学基金及省市各级课题6项。申请国家发明专利1项。近年发表论文30余篇,其中SCI收录的国外专业学术期刊近20篇,参与编写眼科专业著作1部。获广东省科技进步三等奖1项。被评为中山大学医科优秀临床带教老师。